高爾基體自身蛋白GM130抗體 Anti-GM130

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公司名稱 上海田源生物技術(shù)有限公司
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更新時(shí)間 2018/5/6 19:30:36
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高爾基體自身蛋白GM130抗體 Anti-GM130 一抗

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上海田源生物技術(shù)有限公司 Shanghai Tiyo Biotechnology Co,ltd.

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高爾基體自身蛋白GM130抗體Anti-GM130的產(chǎn)品說明（為您現(xiàn)貨供應(yīng)，詳詢）：
--產(chǎn)品介紹：The docking of transport vesicles to their target membrane is mediated by p115. GM130, a cis-Golgi matrix protein, interacts specifically with p115 and provides a membrane docking site. Both GM130 and p115 are involved in vesicle tethering to Golgi membranes. The amino-terminus of GM130 binds to p115, whereas the carboxy-terminus binds to Golgi membranes. Both Giantin and GM130 compete for binding to p115. Thus, p115-Giantin and p115-GM130 interactions might mediate independent membrane tethering events. Transport from the ER to the cis/medial Golgi compartments requires the action of p115, GM130 and Giantin via a sequential rather than a coordinate mechanism. Mitotic phosphorylation of GM130 at Serine 25 is mediated by Cdc2, prevents binding to p115 and is directly involved in mitotic Golgi fragmentation. GM130 is phosphorylated in prophase as the Golgi complex starts to break down, and remains phosphorylated in metaphase and anaphase. In ophase, GM130 is dephosphorylated by PP2A as the Golgi fragments start to reassemble.Subcellular Location : Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.Similarity : Belongs to the GOLGA2 family.Subunit : Part of a larger oligomeric complex. Interacts with p115. Interacts with RAB1B that has been activated by GTP-binding. Interacts with GORASP1/GRASP65 and ZFPL1.
--該抗體來源于：（Rabbit）
--高爾基體自身蛋白GM130抗體的參數(shù)介紹：
1、濃度：1mg/1ml
2、交叉反應(yīng)：hu, mo, rat, cow, pig
3、產(chǎn)品類型：一抗
4、研究領(lǐng)域：細(xì)胞生物免疫學(xué)細(xì)胞類型標(biāo)志物
5、蛋白分子量：predicted molecular weight: 110kDa
6、性狀：Lyophilized or Liquid
7、免疫原：KLH conjugated synthetic peptide derived from human GM130
8、亞型：polyclonal
9、純化方法：affinity purified by Protein A
10、儲(chǔ)存液：Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
11、產(chǎn)品應(yīng)用：WB=1:100-500ELISA=1:500-1000IP=1:20-100IHC-P=1:100-500IHC-F=1:100-500IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
12、保存條件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

（1mg/1ml高爾基體自身蛋白GM130抗體Anti-GM130，的相關(guān)產(chǎn)品：免疫組化常用試劑免疫印跡常用試劑各種標(biāo)記二抗）