深圳遠(yuǎn)揚(yáng)化學(xué)技術(shù)有限公司
中級(jí)會(huì)員 | 第10年

15012456311

達(dá)比加群酯雜質(zhì)新藥申報(bào)用

時(shí)間：2017/2/24閱讀：1165
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       達(dá)比加群酯是zui前沿的新一代口服抗凝藥物直接凝血酶抑制劑(DTIs)，用于預(yù)防非瓣膜性房顫患者的卒中和全身性栓塞。達(dá)比加群酯可提供有效的、可預(yù)測(cè)的、穩(wěn)定的抗凝效果，同時(shí)較少發(fā)生藥物相互作用，無(wú)藥物食物相互作用，無(wú)需常規(guī)進(jìn)行凝血功能監(jiān)測(cè)或劑量調(diào)整。

       深圳遠(yuǎn)揚(yáng)化學(xué)可提供達(dá)比加群酯申報(bào)所用全套雜質(zhì)， 進(jìn)口國(guó)產(chǎn)均有銷(xiāo)售，隨貨附CoA證書(shū)，HNMR，MS，HPLC圖譜，純度符合申報(bào)要求。另外，我司有自主實(shí)驗(yàn)室，可提供達(dá)比加群酯雜質(zhì)定制服務(wù)，如以上列表無(wú)您需要的雜質(zhì)，我司詳詢（請(qǐng)點(diǎn)擊本頁(yè)標(biāo)題下方，進(jìn)入該公司展臺(tái)查看我司信息）。

Dabigatran3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acidC25H25N7O3471.51
Dabigatran Impurity 1ethyl 3-(2-(iminomethyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC20H21N5O3379.41
Dabigatran Impurity 23-(2-(((4-(N-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acidC32H37N7O5599.68
Dabigatran Impurity 3ethyl 3-(1-methyl-3-oxo-N-(pyridin-2-yl)-1,2,3,4-tetrahydroquinoxaline-6-carboxamido)propanoateC20H22N4O4382.41
Dabigatran Impurity 4methyl 3-(2-(hydroxymethyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC19H20N4O4368.39
Dabigatran Impurity 53-(2-(chloromethyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acidC18H17ClN4O3372.81
Dabigatran Impurity 6diethyl 3,3'-((2,2'-(oxybis(methylene))bis(1-methyl-1H-benzo[d]imidazole-5,5'-carbonyl))bis(pyridin-2-ylazanediyl))dipropanoateC40H42N8O7746.32
Dabigatran Impurity 7hexyl (imino(4-(((1-methyl-5-(pyridin-2-ylcarbamoyl)-1H-benzo[d]imidazol-2-yl)methyl)amino)phenyl)methyl)carbamateC29H33N7O3527.62
Dabigatran Impurity 8(Z)-3-(2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoic acidC32H37N7O5599.68
Dabigatran Impurity 9ethyl 3-(2-(((4-(((hexyloxy)carbonyl)carbamoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC34H40N6O6628.72
Dabigatran Impurity 10(Z)-ethyl 3-(2-(((4-(N'-((hexan-2-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC34H41N7O5627.73
Dabigatran Impurity 11(Z)-ethyl 3-(2-(((4-(N'-((hexan-3-yloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC34H41N7O5627.73
Dabigatran Impurity 12ethyl 3-(1,2-dimethyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC20H22N4O3366.41
Dabigatran Impurity 13ethyl 3-(1-methyl-2-oxo-N-(pyridin-2-yl)-2,3-dihydro-1H-benzo[d]imidazole-5-carboxamido)propanoateC19H20N4O4368.39
Dabigatran Impurity 14(Z)-ethyl 2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-1H-benzo[d]imidazole-5-carboxylateC26H33N5O4479.57
Dabigatran Impurity 15ethyl 3-(2-(((4-cyanophenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC27H26N6O3482.53
Dabigatran Impurity 16ethyl 3-(2-(((4-(ethoxy(imino)methyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochlorideC29H32N6O4·HCl565.06
Dabigatran Impurity 17(Z)-methyl 3-(2-(((4-(N'-((hexyloxy)carbonyl)carbamimidoyl)phenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC33H39N7O5613.71
Dabigatran Impurity 18(Z)-hexyl (amino(4-(((5-((3-amino-3-oxopropyl)(pyridin-2-yl)carbamoyl)-1-methyl-1H-benzo[d]imidazol-2-yl)methyl)amino)phenyl)methylene)carbamateC32H38N8O4598.70
Dabigatran Impurity 19ethyl 3-(2-(((4-carbamoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoateC27H28N6O4500.55
Dabigatran Impurity 20ethyl 3-(2-(((4-carbamimidoylphenyl)amino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate hydrochlorideC27H29N7O3·HCl536.03
Dabigatran Impurity 21ethyl 3-(3-amino-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoateC18H22N4O3342.39
Dabigatran Impurity 22ethyl 3-(3-(2-((4-cyanophenyl)amino)acetamido)-4-(methylamino)-N-(pyridin-2-yl)benzamido)propanoateC27H28N6O4

500.55

 

達(dá)比加群酯雜質(zhì)新藥申報(bào)用結(jié)構(gòu)式歡迎我司獲取~

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